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Multi-clonal evolution of multi-drug-resistant/extensively drug-resistant Mycobacterium tuberculosis in a high-prevalence setting of Papua New Guinea for over three decades

An outbreak of multi-drug resistant (MDR) tuberculosis (TB) has been reported on Daru Island, Papua New Guinea. Mycobacterium tuberculosis strains driving this outbreak and the temporal accrual of drug resistance mutations have not been described. Whole genome sequencing of 100 of 165 clinical isola...

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Detalles Bibliográficos
Autores principales: Bainomugisa, Arnold, Lavu, Evelyn, Hiashiri, Stenard, Majumdar, Suman, Honjepari, Alice, Moke, Rendi, Dakulala, Paison, Hill-Cawthorne, Grant A., Pandey, Sushil, Marais, Ben J., Coulter, Chris, Coin, Lachlan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857374/
https://www.ncbi.nlm.nih.gov/pubmed/29310751
http://dx.doi.org/10.1099/mgen.0.000147