Distinct Shift in Beta-Cell Glutaredoxin 5 Expression Is Mediated by Hypoxia and Lipotoxicity Both In Vivo and In Vitro

Histomorphological and functional alterations in pancreatic islet composition directly correlate with hyperglycemia severity. Progressive deterioration of metabolic control in subjects suffering from type 2 diabetes is predominantly caused by impaired beta-cell functionality. The glutaredoxin system...

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Detalles Bibliográficos
Autores principales: Petry, Sebastian Friedrich, Sun, Lia Mingzhe, Knapp, Anna, Reinl, Sabrina, Linn, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857561/
https://www.ncbi.nlm.nih.gov/pubmed/29593651
http://dx.doi.org/10.3389/fendo.2018.00084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857561/
https://www.ncbi.nlm.nih.gov/pubmed/29593651
http://dx.doi.org/10.3389/fendo.2018.00084

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