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Computational Insight Into the Structural Organization of Full-Length Toll-Like Receptor 4 Dimer in a Model Phospholipid Bilayer

Toll-like receptors (TLRs) are a unique category of pattern recognition receptors that recognize distinct pathogenic components, often utilizing the same set of downstream adaptors. Specific molecular features of extracellular, transmembrane (TM), and cytoplasmic domains of TLRs are crucial for coor...

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Detalles Bibliográficos
Autores principales: Patra, Mahesh Chandra, Kwon, Hyuk-Kwon, Batool, Maria, Choi, Sangdun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857566/
https://www.ncbi.nlm.nih.gov/pubmed/29593733
http://dx.doi.org/10.3389/fimmu.2018.00489