Mob2 Insufficiency Disrupts Neuronal Migration in the Developing Cortex

Disorders of neuronal mispositioning during brain development are phenotypically heterogeneous and their genetic causes remain largely unknown. Here, we report biallelic variants in a Hippo signaling factor—MOB2—in a patient with one such disorder, periventricular nodular heterotopia (PH). Genetic a...

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Detalles Bibliográficos
Autores principales: O’Neill, Adam C., Kyrousi, Christina, Einsiedler, Melanie, Burtscher, Ingo, Drukker, Micha, Markie, David M., Kirk, Edwin P., Götz, Magdalena, Robertson, Stephen P., Cappello, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857600/
https://www.ncbi.nlm.nih.gov/pubmed/29593499
http://dx.doi.org/10.3389/fncel.2018.00057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857600/
https://www.ncbi.nlm.nih.gov/pubmed/29593499
http://dx.doi.org/10.3389/fncel.2018.00057

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