Mutations in the β-amyloid precursor protein in familial Alzheimer’s disease increase Aβ oligomer production in cellular models

Soluble oligomers of amyloid-β (Aβ) peptides (AβOs) contribute to neurotoxicity in Alzheimer’s disease (AD). However, it currently remains unknown whether an increase in AβOs is the common phenotype in cellular and animal models. Furthermore, it has not yet been established whether experimental stud...

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Detalles Bibliográficos
Autores principales: Ohshima, Yoichi, Taguchi, Katsutoshi, Mizuta, Ikuko, Tanaka, Masaki, Tomiyama, Takami, Kametani, Fuyuki, Yabe-Nishimura, Chihiro, Mizuno, Toshiki, Tokuda, Takahiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857613/
https://www.ncbi.nlm.nih.gov/pubmed/29560429
http://dx.doi.org/10.1016/j.heliyon.2018.e00511

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857613/
https://www.ncbi.nlm.nih.gov/pubmed/29560429
http://dx.doi.org/10.1016/j.heliyon.2018.e00511

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