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Branched chain amino acids attenuate major pathologies in mouse models of retinal degeneration and glaucoma

Retinal neuronal cell death underlies many incurable eye diseases such as retinitis pigmentosa (RP) and glaucoma, and causes adult blindness. We have shown that maintenance of ATP levels via inhibiting ATP consumption is a promising strategy for preventing neuronal cell death. Here, we show that bra...

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Detalles Bibliográficos
Autores principales: Hasegawa, Tomoko, Ikeda, Hanako Ohashi, Iwai, Sachiko, Muraoka, Yuki, Tsuruyama, Tatsuaki, Okamoto-Furuta, Keiko, Kohda, Haruyasu, Kakizuka, Akira, Yoshimura, Nagahisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857634/
https://www.ncbi.nlm.nih.gov/pubmed/29560458
http://dx.doi.org/10.1016/j.heliyon.2018.e00544