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Randomised controlled trial protocol to evaluate a fixed dose prothrombin complex concentrate against the variable dose in vitamin K antagonist related bleeding (PROPER3)

INTRODUCTION: There is currently little evidence for the optimal dosing strategy of four-factor prothrombin complex concentrates (PCC) in vitamin K antagonist (VKA)-related bleeds. The generally accepted dosing strategy is the use of a variable dose calculated using patient-specific characteristics...

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Detalles Bibliográficos
Autores principales: Abdoellakhan, Rahat A, Khorsand, Nakisa, Van Hest, Reinier M, Veeger, Nic, Ter Avest, Ewoud, Ypma, Paula F, Faber, Laura M, Meijer, Karina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857685/
https://www.ncbi.nlm.nih.gov/pubmed/29540424
http://dx.doi.org/10.1136/bmjopen-2017-020764