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Anarchy in the UPR: a Ca(2+)-insensitive PKC inhibits SERCA activity to promote ER stress

Nonalcoholic fatty liver disease (NAFLD) is highly prevalent in Western countries, and is linked to the development of liver cancer and Type 2 diabetes (T2D). It is strongly associated with obesity, but the dysregulation of liver lipid storage is not fully understood. Fatty acid oversupply to hepato...

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Detalles Bibliográficos
Autor principal: Schmitz-Peiffer, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857902/
https://www.ncbi.nlm.nih.gov/pubmed/29439143
http://dx.doi.org/10.1042/BSR20170966