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Unraveling Tetrazine-Triggered Bioorthogonal Elimination Enables Chemical Tools for Ultrafast Release and Universal Cleavage

[Image: see text] Recent developments in bond cleavage reactions have expanded the scope of bioorthogonal chemistry beyond click ligation and enabled new strategies for probe activation and therapeutic delivery. These applications, however, remain in their infancy, with further innovations needed to...

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Detalles Bibliográficos
Autores principales: Carlson, Jonathan C. T., Mikula, Hannes, Weissleder, Ralph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857921/
https://www.ncbi.nlm.nih.gov/pubmed/29384666
http://dx.doi.org/10.1021/jacs.7b11217