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Amyloid β-peptides 1–40 and 1–42 form oligomers with mixed β-sheets

Two main amyloid-β peptides of different length (Aβ(40) and Aβ(42)) are involved in Alzheimer's disease. Their relative abundance is decisive for the severity of the disease and mixed oligomers may contribute to the toxic species. However, little is know about the extent of mixing. To study whe...

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Detalles Bibliográficos
Autores principales: Baldassarre, Maurizio, Baronio, Cesare M., Morozova-Roche, Ludmilla A., Barth, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857929/
https://www.ncbi.nlm.nih.gov/pubmed/29568473
http://dx.doi.org/10.1039/c7sc01743j