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Fluoro-substituted cyanine for reliable in vivo labelling of amyloid-β oligomers and neuroprotection against amyloid-β induced toxicity

Alzheimer’s disease (AD) is the most prevalent but still incurable neurodegenerative form of dementia. Early diagnosis and intervention are crucial for delaying the onset and progression of the disease. We herein report a novel fluoro-substituted cyanine, F-SLOH, which exhibits good Aβ oligomer sele...

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Detalles Bibliográficos
Autores principales: Li, Yinhui, Xu, Di, Sun, Anyang, Ho, See-Lok, Poon, Chung-Yan, Chan, Hei-Nga, Ng, Olivia T. W., Yung, Ken K. L., Yan, Hui, Li, Hung-Wing, Wong, Man Shing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858019/
https://www.ncbi.nlm.nih.gov/pubmed/29619173
http://dx.doi.org/10.1039/c7sc03974c