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Fluoro-substituted cyanine for reliable in vivo labelling of amyloid-β oligomers and neuroprotection against amyloid-β induced toxicity
Alzheimer’s disease (AD) is the most prevalent but still incurable neurodegenerative form of dementia. Early diagnosis and intervention are crucial for delaying the onset and progression of the disease. We herein report a novel fluoro-substituted cyanine, F-SLOH, which exhibits good Aβ oligomer sele...
Autores principales: | Li, Yinhui, Xu, Di, Sun, Anyang, Ho, See-Lok, Poon, Chung-Yan, Chan, Hei-Nga, Ng, Olivia T. W., Yung, Ken K. L., Yan, Hui, Li, Hung-Wing, Wong, Man Shing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858019/ https://www.ncbi.nlm.nih.gov/pubmed/29619173 http://dx.doi.org/10.1039/c7sc03974c |
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