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In Vitro Model-Systems to Understand the Biology and Clinical Significance of Circulating Tumor Cell Clusters

The isolation of clusters of circulating tumor cells (CTCs) from cancer patients has recently challenged the accepted view that the initiation of secondary tumors during metastasis involves the dissemination of individual cancer cells. As such clusters appear to be more aggressive than single tumor...

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Detalles Bibliográficos
Autores principales: May, Alexander N., Crawford, Bryan D., Nedelcu, Aurora M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858030/
https://www.ncbi.nlm.nih.gov/pubmed/29594043
http://dx.doi.org/10.3389/fonc.2018.00063