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XIAP Limits Autophagic Degradation of Sox2 and Is A Therapeutic Target in Nasopharyngeal Carcinoma Stem Cells

Rationale: Nasopharyngeal carcinoma (NPC) is the most frequent head and neck tumor in South China. The presence of cancer stem cells (CSCs) in NPC contributes to tumor maintenance and therapeutic resistance, while the ability of CSCs to escape from the apoptosis pathway may render them the resistant...

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Detalles Bibliográficos
Autores principales: Ji, Jiao, Yu, Yan, Li, Zhi-Ling, Chen, Ming-Yuan, Deng, Rong, Huang, Xiang, Wang, Guang-Feng, Zhang, Meng-Xia, Yang, Qi, Ravichandran, Senthilkumar, Feng, Gong-Kan, Xu, Xue-Lian, Yang, Chen-Lu, Qiu, Miao-Zhen, Jiao, Lin, Yang, Dajun, Zhu, Xiao-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858163/
https://www.ncbi.nlm.nih.gov/pubmed/29556337
http://dx.doi.org/10.7150/thno.21717