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Rhubarb attenuates cerebral edema via inhibition of the extracellular signal-regulated kinase pathway following traumatic brain injury in rats

BACKGROUND: Rhubarb is a traditional Chinese medicine for treating traumatic brain injury (TBI). PURPOSE: The purpose of this study is to elucidate the potential mechanism of rhubarb by suppressing extracellular signal-regulated kinase (ERK) to ameliorate brain edema. MATERIALS AND METHODS: Sprague-...

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Detalles Bibliográficos
Autores principales: Yang, Zhaoyu, Fan, Rong, Sun, Peng, Cui, Hanjin, Peng, Weijun, Luo, Jiekun, Zhang, Chunhu, Xiong, Xingui, Huang, Wei, Liu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858234/
https://www.ncbi.nlm.nih.gov/pubmed/29576714
http://dx.doi.org/10.4103/pm.pm_218_17