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Demethoxycurcumin, a Natural Derivative of Curcumin Abrogates Rotenone-induced Dopamine Depletion and Motor Deficits by Its Antioxidative and Anti-inflammatory Properties in Parkinsonian Rats

BACKGROUND: Parkinson's disease (PD) is a progressive neurodegenerative disorder (NDD) associated with the loss of dopaminergic neurons in the substantia nigra and subsequently has an effect on motor function and coordination. The pathology of PD is multifactorial, in which neuroinflammation an...

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Detalles Bibliográficos
Autores principales: Ramkumar, Muthu, Rajasankar, Srinivasagam, Gobi, Veerapan Venkatesh, Janakiraman, Udaiyappan, Manivasagam, Thamilarasan, Thenmozhi, Arokiasamy Justin, Essa, Musthafa Mohamed, Chidambaram, Ranganathan, Chidambaram, Saravana Babu, Guillemin, Giles J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858249/
https://www.ncbi.nlm.nih.gov/pubmed/29576695
http://dx.doi.org/10.4103/pm.pm_113_17