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Demethoxycurcumin, a Natural Derivative of Curcumin Abrogates Rotenone-induced Dopamine Depletion and Motor Deficits by Its Antioxidative and Anti-inflammatory Properties in Parkinsonian Rats
BACKGROUND: Parkinson's disease (PD) is a progressive neurodegenerative disorder (NDD) associated with the loss of dopaminergic neurons in the substantia nigra and subsequently has an effect on motor function and coordination. The pathology of PD is multifactorial, in which neuroinflammation an...
Autores principales: | Ramkumar, Muthu, Rajasankar, Srinivasagam, Gobi, Veerapan Venkatesh, Janakiraman, Udaiyappan, Manivasagam, Thamilarasan, Thenmozhi, Arokiasamy Justin, Essa, Musthafa Mohamed, Chidambaram, Ranganathan, Chidambaram, Saravana Babu, Guillemin, Giles J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858249/ https://www.ncbi.nlm.nih.gov/pubmed/29576695 http://dx.doi.org/10.4103/pm.pm_113_17 |
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