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The Role of Wnt/β-Catenin Signaling and K-Cadherin in the Regulation of Intraocular Pressure

PURPOSE: Wnt/β-catenin signaling in the trabecular meshwork (TM) is required for maintaining normal intraocular pressure (IOP), although the mechanism(s) behind this are unknown. We hypothesize that Wnt/β-catenin signaling regulates IOP via β-catenin's effects on cadherin junctions. METHODS: No...

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Detalles Bibliográficos
Autores principales: Webber, Hannah C., Bermudez, Jaclyn Y., Millar, J. Cameron, Mao, Weiming, Clark, Abbot F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858463/
https://www.ncbi.nlm.nih.gov/pubmed/29625468
http://dx.doi.org/10.1167/iovs.17-21964