Palmatine suppresses glutamine-mediated interaction between pancreatic cancer and stellate cells through simultaneous inhibition of survivin and COL1A1

Reciprocal interaction between pancreatic stellate cells (PSCs) and cancer cells (PCCs) in the tumor microenvironment (TME) promotes tumor cell survival and progression to lethal, therapeutically resistant pancreatic cancer. The goal of this study was to test the ability of Palmatine (PMT) to disrup...

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Detalles Bibliográficos
Autores principales: Chakravarthy, Divya, Muñoz, Amanda R., Su, Angel, Hwang, Rosa F., Keppler, Brian R., Chan, Daniel E., Halff, Glenn, Ghosh, Rita, Kumar, Addanki P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858579/
https://www.ncbi.nlm.nih.gov/pubmed/29414301
http://dx.doi.org/10.1016/j.canlet.2018.01.057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858579/
https://www.ncbi.nlm.nih.gov/pubmed/29414301
http://dx.doi.org/10.1016/j.canlet.2018.01.057

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