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siRNA-loaded selenium nanoparticle modified with hyaluronic acid for enhanced hepatocellular carcinoma therapy

BACKGROUND: Small interfering RNA (siRNA) as a new therapeutic modality holds promise for cancer treatment. However, the traditional viral carriers are prone to immunogenicity and risk of insertional mutagenesis. METHODS: In order to provide a tumor-targeted delivery carrier of siRNA in cancer thera...

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Detalles Bibliográficos
Autores principales: Xia, Yu, Guo, Min, Xu, Tiantian, Li, Yinghua, Wang, Changbing, Lin, Zhengfang, Zhao, Mingqi, Zhu, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858822/
https://www.ncbi.nlm.nih.gov/pubmed/29588583
http://dx.doi.org/10.2147/IJN.S157519