Cargando…

siRNA-loaded selenium nanoparticle modified with hyaluronic acid for enhanced hepatocellular carcinoma therapy

BACKGROUND: Small interfering RNA (siRNA) as a new therapeutic modality holds promise for cancer treatment. However, the traditional viral carriers are prone to immunogenicity and risk of insertional mutagenesis. METHODS: In order to provide a tumor-targeted delivery carrier of siRNA in cancer thera...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xia, Yu, Guo, Min, Xu, Tiantian, Li, Yinghua, Wang, Changbing, Lin, Zhengfang, Zhao, Mingqi, Zhu, Bing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858822/ https://www.ncbi.nlm.nih.gov/pubmed/29588583 http://dx.doi.org/10.2147/IJN.S157519

Ejemplares similares

Targeted delivery of HES5-siRNA with novel polypeptide-modified nanoparticles for hepatocellular carcinoma therapy
por: Xia, Yu, et al.
Publicado: (2018)

Multifunctional selenium nanoparticles as carriers of HSP70 siRNA to induce apoptosis of HepG2 cells
por: Li, Yinghua, et al.
Publicado: (2016)

Folate-targeted selenium nanoparticles deliver therapeutic siRNA to improve hepatocellular carcinoma therapy
por: Xia, Yu, et al.
Publicado: (2018)

Inhibition of Enterovirus 71 by Selenium Nanoparticles Loaded with siRNA through Bax Signaling Pathways
por: Lin, Zhengfang, et al.
Publicado: (2020)

Novel functionalized nanoparticles for tumor-targeting co-delivery of doxorubicin and siRNA to enhance cancer therapy
por: Xia, Yu, et al.
Publicado: (2017)

Silencing of MEF2D by siRNA Loaded Selenium Nanoparticles for Ovarian Cancer Therapy
por: Wang, Changbing, et al.
Publicado: (2020)

Galactose-modified selenium nanoparticles for targeted delivery of doxorubicin to hepatocellular carcinoma
por: Xia, Yu, et al.
Publicado: (2019)

Inhibitory activity of selenium nanoparticles functionalized with oseltamivir on H1N1 influenza virus
por: Li, Yinghua, et al.
Publicado: (2017)

Multifunctional selenium nanoparticles with Galangin-induced HepG2 cell apoptosis through p38 and AKT signalling pathway
por: Li, Yinghua, et al.
Publicado: (2018)

Inhibition of H1N1 influenza virus-induced apoptosis by functionalized selenium nanoparticles with amantadine through ROS-mediated AKT signaling pathways
por: Li, Yinghua, et al.
Publicado: (2018)

Tumor-targeted delivery of siRNA to silence Sox2 gene expression enhances therapeutic response in hepatocellular carcinoma
por: Xia, Yu, et al.
Publicado: (2020)

Functionalized selenium nanoparticles for targeted siRNA delivery silence Derlin1 and promote antitumor efficacy against cervical cancer
por: Xia, Yu, et al.
Publicado: (2019)

Delivery of Doxorubicin for Human Cervical Carcinoma Targeting Therapy by Folic Acid-Modified Selenium Nanoparticles
por: Xia, Yu, et al.
Publicado: (2018)

Functionalized selenium nanoparticles for targeted delivery of doxorubicin to improve non-small-cell lung cancer therapy
por: Xia, Yu, et al.
Publicado: (2018)

Silver Nanoparticles Induce HePG-2 Cells Apoptosis Through ROS-Mediated Signaling Pathways
por: Zhu, Bing, et al.
Publicado: (2016)

Restriction of H1N1 influenza virus infection by selenium nanoparticles loaded with ribavirin via resisting caspase-3 apoptotic pathway
por: Lin, Zhengfang, et al.
Publicado: (2018)

The Inhibition of H1N1 Influenza Virus-Induced Apoptosis by Surface Decoration of Selenium Nanoparticles with β-Thujaplicin through Reactive Oxygen Species-Mediated AKT and p53 Signaling Pathways
por: Wang, Changbing, et al.
Publicado: (2020)

Polyethylenimine-functionalized silver nanoparticle-based co-delivery of paclitaxel to induce HepG2 cell apoptosis
por: Li, Yinghua, et al.
Publicado: (2016)

Antitumor effect of hyaluronic-acid-modified chitosan nanoparticles loaded with siRNA for targeted therapy for non-small cell lung cancer
por: Zhang, Wenhua, et al.
Publicado: (2019)

Construction of Hyaluronic Tetrasaccharide Clusters Modified Polyamidoamine siRNA Delivery System
por: Ma, Yingcong, et al.
Publicado: (2018)

Hyaluronic acid-modified redox-sensitive hybrid nanocomplex loading with siRNA for non-small-cell lung carcinoma therapy
por: Chen, Daoyuan, et al.
Publicado: (2022)

Inhibition of H3N2 Influenza Virus Induced Apoptosis by Selenium Nanoparticles with Chitosan through ROS-Mediated Signaling Pathways
por: Xu, Tiantian, et al.
Publicado: (2023)

Engineering siRNA-loaded and RGDfC-targeted selenium nanoparticles for highly efficient silencing of DCBLD2 gene for colorectal cancer treatment
por: Huang, Hongli, et al.
Publicado: (2023)

Superparamagnetic iron oxide nanoparticles modified with polyethylenimine and galactose for siRNA targeted delivery in hepatocellular carcinoma therapy
por: Yang, Zhen, et al.
Publicado: (2018)

Albumin pre-coating enhances intracellular siRNA delivery of multifunctional amphiphile/siRNA nanoparticles
por: Kummitha, China M, et al.
Publicado: (2012)

MDR1 siRNA loaded hyaluronic acid-based CD44 targeted nanoparticle systems circumvent paclitaxel resistance in ovarian cancer
por: Yang, Xiaoqian, et al.
Publicado: (2015)

Hyaluronic Acid-Modified and Doxorubicin-Loaded Gold Nanoparticles and Evaluation of Their Bioactivity
por: Li, Lin-Song, et al.
Publicado: (2021)

Characterization of modified mesoporous silica nanoparticles as vectors for siRNA delivery
por: Slita, Anna, et al.
Publicado: (2018)

Enzyme-triggered PEGylated siRNA-nanoparticles for controlled release of siRNA
por: Yingyuad, Peerada, et al.
Publicado: (2014)

Selenium nanoparticles inhibited H1N1 influenza virus-induced apoptosis by ROS-mediated signaling pathways
por: Liu, Xia, et al.
Publicado: (2022)

Polymerized Selenium Nanoparticles for Folate-Receptor-Targeted Delivery of Anti-Luc-siRNA: Potential for Gene Silencing
por: Maiyo, Fiona, et al.
Publicado: (2020)

Silver Nanoparticles Surface-Modified with Carbosilane Dendrons as Carriers of Anticancer siRNA
por: Pędziwiatr-Werbicka, Elżbieta, et al.
Publicado: (2020)

Cell-Penetrating Peptide-Modified Graphene Oxide Nanoparticles Loaded with Rictor siRNA for the Treatment of Triple-Negative Breast Cancer
por: Yang, Yun-Yun, et al.
Publicado: (2021)

Novel targeted siRNA-loaded hybrid nanoparticles: preparation, characterization and in vitro evaluation
por: Dim, Nneka, et al.
Publicado: (2015)

Local delivery of siRNA-loaded calcium phosphate nanoparticles abates pulmonary inflammation
por: Frede, Annika, et al.
Publicado: (2017)

Effective Delivery of siRNA-Loaded Nanoparticles for Overcoming Oxaliplatin Resistance in Colorectal Cancer
por: Zhou, Yue, et al.
Publicado: (2022)

Effect of Cationic Lipid Nanoparticle Loaded siRNA with Stearylamine against Chikungunya Virus
por: Jeengar, Manish Kumar, et al.
Publicado: (2022)

Protection and Systemic Translocation of siRNA Following Oral Administration of Chitosan/siRNA Nanoparticles
por: Ballarín-González, Borja, et al.
Publicado: (2013)

Cyclic Peptide-Capped Gold Nanoparticles for Enhanced siRNA Delivery
por: Shirazi, Amir Nasrolahi, et al.
Publicado: (2014)

Natural Polysaccharides for siRNA Delivery: Nanocarriers Based on Chitosan, Hyaluronic Acid, and Their Derivatives
por: Serrano-Sevilla, Inés, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_8sfclr8ih3qijgcr8c9t8rbce1