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siRNA-loaded selenium nanoparticle modified with hyaluronic acid for enhanced hepatocellular carcinoma therapy
BACKGROUND: Small interfering RNA (siRNA) as a new therapeutic modality holds promise for cancer treatment. However, the traditional viral carriers are prone to immunogenicity and risk of insertional mutagenesis. METHODS: In order to provide a tumor-targeted delivery carrier of siRNA in cancer thera...
Autores principales: | Xia, Yu, Guo, Min, Xu, Tiantian, Li, Yinghua, Wang, Changbing, Lin, Zhengfang, Zhao, Mingqi, Zhu, Bing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858822/ https://www.ncbi.nlm.nih.gov/pubmed/29588583 http://dx.doi.org/10.2147/IJN.S157519 |
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