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The severity of imiquimod-induced mouse skin inflammation is independent of endogenous IL-38 expression

The IL-1 cytokine family includes eleven members, among which Il-36α, β and γ, IL-36Ra and IL-38. The IL-36 cytokines are involved in the pathogenesis of psoriasis. IL-38 is also expressed in the skin and was previously proposed to act as an IL-36 antagonist. In this study, we thus examined expressi...

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Detalles Bibliográficos
Autores principales: Palomo, Jennifer, Troccaz, Sabina, Talabot-Ayer, Dominique, Rodriguez, Emiliana, Palmer, Gaby
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858842/
https://www.ncbi.nlm.nih.gov/pubmed/29554104
http://dx.doi.org/10.1371/journal.pone.0194667