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PRDM14 is expressed in germ cell tumors with constitutive overexpression altering human germline differentiation and proliferation

Germ cell tumors (GCTs) are a heterogeneous group of tumors occurring in gonadal and extragonadal locations. GCTs are hypothesized to arise from primordial germ cells (PGCs), which fail to differentiate. One recently identified susceptibility loci for human GCT is PR (PRDI-BF1 and RIZ) domain protei...

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Detalles Bibliográficos
Autores principales: Gell, Joanna J., Zhao, Jasmine, Chen, Di, Hunt, Timothy J., Clark, Amander T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858915/
https://www.ncbi.nlm.nih.gov/pubmed/29324254
http://dx.doi.org/10.1016/j.scr.2017.12.016