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Multiplexed imaging of high-density libraries of RNAs with MERFISH and expansion microscopy
As an image-based single-cell transcriptomics approach, multiplexed error-robust fluorescence in situ hybridization (MERFISH) allows hundreds to thousands of RNA species to be identified, counted and localized in individual cells while preserving the native spatial context of RNAs. In MERFISH, RNAs...
Autores principales: | Wang, Guiping, Moffitt, Jeffrey R., Zhuang, Xiaowei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859009/ https://www.ncbi.nlm.nih.gov/pubmed/29555914 http://dx.doi.org/10.1038/s41598-018-22297-7 |
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