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Efficacy and Safety of GPR119 Agonist DS-8500a in Japanese Patients with Type 2 Diabetes: a Randomized, Double-Blind, Placebo-Controlled, 12-Week Study

INTRODUCTION: G protein-coupled receptor 119 (GPR119) is a promising target for the treatment of type 2 diabetes mellitus (T2DM), as both insulin and glucagon-like peptide-1 secretion can be promoted with a single drug. We compared the efficacy and safety of the GPR119 agonist DS-8500a with placebo...

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Detalles Bibliográficos
Autores principales: Yamada, Yuichiro, Terauchi, Yasuo, Watada, Hirotaka, Nakatsuka, Yasuhiko, Shiosakai, Kazuhito, Washio, Takuo, Taguchi, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859088/
https://www.ncbi.nlm.nih.gov/pubmed/29488152
http://dx.doi.org/10.1007/s12325-018-0668-2