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Dynamic metabolic patterns tracking neurodegeneration and gliosis following 26S proteasome dysfunction in mouse forebrain neurons

Metabolite profiling is an important tool that may better capture the multiple features of neurodegeneration. With the considerable parallels between mouse and human metabolism, the use of metabolomics in mouse models with neurodegenerative pathology provides mechanistic insight and ready translatio...

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Detalles Bibliográficos
Autores principales: Geiszler, Philippine C., Ugun-Klusek, Aslihan, Lawler, Karen, Pardon, Marie-Christine, Yuchun, Ding, Bai, Li, Daykin, Clare A., Auer, Dorothee P., Bedford, Lynn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859111/
https://www.ncbi.nlm.nih.gov/pubmed/29555943
http://dx.doi.org/10.1038/s41598-018-23155-2