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Effect of nonionic surfactants in release media on accelerated in-vitro release profile of sirolimus eluting stents with biodegradable polymeric coating

It is a well-known fact that sirolimus (SRL) undergoes degradation process via hydrolysis in aqueous media, leading to incorrect assessment of drug amount and thus release characteristics of formulations. The main objective of the present study was to evaluate the effect of nonionic surfactants in m...

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Detalles Bibliográficos
Autores principales: Raval, Ami, Bahadur, Pratap, Raval, Ankur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859125/
https://www.ncbi.nlm.nih.gov/pubmed/29568667
http://dx.doi.org/10.1016/j.jpha.2017.06.002