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Effect of nonionic surfactants in release media on accelerated in-vitro release profile of sirolimus eluting stents with biodegradable polymeric coating
It is a well-known fact that sirolimus (SRL) undergoes degradation process via hydrolysis in aqueous media, leading to incorrect assessment of drug amount and thus release characteristics of formulations. The main objective of the present study was to evaluate the effect of nonionic surfactants in m...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Xi'an Jiaotong University
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859125/ https://www.ncbi.nlm.nih.gov/pubmed/29568667 http://dx.doi.org/10.1016/j.jpha.2017.06.002 |