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A liquid chromatography with tandem mass spectrometry method for quantitating total and unbound ceritinib in patient plasma and brain tumor

A rapid, sensitive, and robust reversed-phase liquid chromatography with tandem mass spectrometry method was developed and validated for the determination of total and unbound ceritinib, a second-generation ALK inhibitor, in patient plasma and brain tumor tissue samples. Sample preparation involved...

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Detalles Bibliográficos
Autores principales: Bao, Xun, Wu, Jianmei, Sanai, Nader, Li, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859147/
https://www.ncbi.nlm.nih.gov/pubmed/29568664
http://dx.doi.org/10.1016/j.jpha.2017.07.007