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Protein Phosphatase Magnesium-Dependent 1δ (PPM1D) Expression as a Prognostic Marker in Adult Supratentorial Diffuse Astrocytic and Oligodendroglial Tumors

BACKGROUND: Protein phosphatase magnesium-dependent 1δ (PPM1D) is a p53-induced serine/threonine phosphatase, which is overexpressed in various human cancers. A recent study reported that a mutation in the PPM1D gene is associated with poor prognosis in brainstem gliomas. In this study, we evaluated...

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Detalles Bibliográficos
Autores principales: Jeong, Hui Jeong, Woo, Chang Gok, Lee, Bora, Khang, Shin Kwang, Nam, Soo Jeong, Choi, Jene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Pathologists and the Korean Society for Cytopathology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859240/
https://www.ncbi.nlm.nih.gov/pubmed/29046514
http://dx.doi.org/10.4132/jptm.2017.10.21