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Androgen receptor modulation following combination exposure to brominated flame-retardants

Endocrine disrupting compounds can interfere with androgen receptor (AR) signaling and disrupt steroidogenesis leading to reproductive failure. The brominated flame-retardant (BFR) 1, 2-dibromo-4-(1, 2-dibromoethyl) cyclohexane (TBECH), is an agonist to human, chicken and zebrafish AR. Recently anot...

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Detalles Bibliográficos
Autores principales: Kharlyngdoh, Joubert Banjop, Pradhan, Ajay, Olsson, Per-Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859252/
https://www.ncbi.nlm.nih.gov/pubmed/29556062
http://dx.doi.org/10.1038/s41598-018-23181-0