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Cancer-associated fibroblasts induce PDL1+ neutrophils through the IL6-STAT3 pathway that foster immune suppression in hepatocellular carcinoma

Emerging evidence indicate that cancer-associated fibroblasts (CAFs) affect tumor progression by reshaping the tumor microenvironment. Neutrophils are prominent components of solid tumors and important in cancer progression. Whether the phenotype and function of neutrophils in hepatocellular carcino...

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Detalles Bibliográficos
Autores principales: Cheng, Yusheng, Li, Hui, Deng, Yinan, Tai, Yan, Zeng, Kaining, Zhang, Yingcai, Liu, Wei, Zhang, Qi, Yang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859264/
https://www.ncbi.nlm.nih.gov/pubmed/29556041
http://dx.doi.org/10.1038/s41419-018-0458-4