Molecular Insights into the Interaction of RONS and Thieno[3,2-c]pyran Analogs with SIRT6/COX-2: A Molecular Dynamics Study

SIRT6 and COX-2 are oncogenes target that promote the expression of proinflammatory and pro-survival proteins through a signaling pathway, which leads to increased survival and proliferation of tumor cells. However, COX-2 also suppresses skin tumorigenesis and their relationship with SIRT6, making i...

Descripción completa

Detalles Bibliográficos
Autores principales: Yadav, Dharmendra K., Kumar, Surendra, Saloni, Misra, Sanjeev, Yadav, Lalit, Teli, Mahesh, Sharma, Praveen, Chaudhary, Sandeep, Kumar, Naresh, Choi, Eun Ha, Kim, Hyung Sik, Kim, Mi-hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859274/
https://www.ncbi.nlm.nih.gov/pubmed/29556059
http://dx.doi.org/10.1038/s41598-018-22972-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859274/
https://www.ncbi.nlm.nih.gov/pubmed/29556059
http://dx.doi.org/10.1038/s41598-018-22972-9

Ejemplares similares