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Molecular Insights into the Interaction of RONS and Thieno[3,2-c]pyran Analogs with SIRT6/COX-2: A Molecular Dynamics Study

SIRT6 and COX-2 are oncogenes target that promote the expression of proinflammatory and pro-survival proteins through a signaling pathway, which leads to increased survival and proliferation of tumor cells. However, COX-2 also suppresses skin tumorigenesis and their relationship with SIRT6, making i...

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Detalles Bibliográficos
Autores principales:	Yadav, Dharmendra K., Kumar, Surendra, Saloni, Misra, Sanjeev, Yadav, Lalit, Teli, Mahesh, Sharma, Praveen, Chaudhary, Sandeep, Kumar, Naresh, Choi, Eun Ha, Kim, Hyung Sik, Kim, Mi-hyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859274/ https://www.ncbi.nlm.nih.gov/pubmed/29556059 http://dx.doi.org/10.1038/s41598-018-22972-9

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