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The Nuclear Orphan Receptor Nur77 Alleviates Palmitate-induced Fat Accumulation by Down-regulating G0S2 in HepG2 Cells

Excessive triglyceride accumulation in hepatocytes is the hallmark of obesity-associated nonalcoholic fatty liver disease (NAFLD). Elevated levels of the saturated free fatty acid palmitate in obesity are a major contributor to excessive hepatic lipid accumulation. The nuclear orphan receptor Nur77...

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Detalles Bibliográficos
Autores principales: Zhao, Naiqian, Li, Xiaoyan, Feng, Ying, Han, Jinxiang, Feng, Ziling, Li, Xifeng, Wen, Yanfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859288/
https://www.ncbi.nlm.nih.gov/pubmed/29556076
http://dx.doi.org/10.1038/s41598-018-23141-8