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Novel biomarker-based model for the prediction of sorafenib response and overall survival in advanced hepatocellular carcinoma: a prospective cohort study

BACKGROUND: Prediction of the outcome of sorafenib therapy using biomarkers is an unmet clinical need in patients with advanced hepatocellular carcinoma (HCC). The aim was to develop and validate a biomarker-based model for predicting sorafenib response and overall survival (OS). METHODS: This prosp...

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Detalles Bibliográficos
Autores principales: Kim, Hwi Young, Lee, Dong Hyeon, Lee, Jeong-Hoon, Cho, Young Youn, Cho, Eun Ju, Yu, Su Jong, Kim, Yoon Jun, Yoon, Jung-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859435/
https://www.ncbi.nlm.nih.gov/pubmed/29558905
http://dx.doi.org/10.1186/s12885-018-4211-2