Cargando…

Involvement of methylation of MicroRNA-122, −125b and -106b in regulation of Cyclin G1, CAT-1 and STAT3 target genes in isoniazid-induced liver injury

BACKGROUND: This investigation aimed to evaluate the role of methylation in the regulation of microRNA (miR)-122, miR-125b and miR-106b gene expression and the expression of their target genes during isoniazid (INH)-induced liver injury. METHODS: Rats were given INH 50 mg kg(− 1)·d(− 1) once per day...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Yuhong, Ren, Qi, Zhu, Lingyan, Li, Yingshu, Li, Jinfeng, Zhang, Yiyang, Zheng, Guoying, Han, Tiesheng, Sun, Shufeng, Feng, Fumin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859513/
https://www.ncbi.nlm.nih.gov/pubmed/29554950
http://dx.doi.org/10.1186/s40360-018-0201-x