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The in vitro effects of a novel estradiol analog on cell proliferation and morphology in human epithelial cervical carcinoma

BACKGROUND: The majority of novel chemotherapeutics target the cell cycle, aiming to effect arrest and cause apoptosis. One such agent, 2-methoxyestradiol (2ME), has been shown to possess anticancer properties against numerous cancer types, both in vitro and in vivo. Despite its promise, 2ME has exh...

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Detalles Bibliográficos
Autores principales: Boyd, Laura Susan, Gozuacik, Devrim, Joubert, Anna Margaretha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859677/
https://www.ncbi.nlm.nih.gov/pubmed/29568313
http://dx.doi.org/10.1186/s11658-018-0079-z