Evaluation of cebranopadol, a dually acting nociceptin/orphanin FQ and opioid receptor agonist in mouse models of acute, tonic, and chemotherapy-induced neuropathic pain

BACKGROUND: Cebranopadol (a.k.a. GRT-6005) is a dually acting nociceptin/orphanin FQ and opioid receptor agonist that has been recently developed in Phase 2 clinical trials for painful diabetic neuropathy or cancer pain. It also showed analgesic properties in various rat models of pain and had a bet...

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Detalles Bibliográficos
Autores principales: Sałat, Kinga, Furgała, Anna, Sałat, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859690/
https://www.ncbi.nlm.nih.gov/pubmed/29071457
http://dx.doi.org/10.1007/s10787-017-0405-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859690/
https://www.ncbi.nlm.nih.gov/pubmed/29071457
http://dx.doi.org/10.1007/s10787-017-0405-5

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