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Engineering T7 bacteriophage as a potential DNA vaccine targeting delivery vector

BACKGROUND: DNA delivery with bacteriophage by surface-displayed mammalian cell penetrating peptides has been reported. Although, various phages have been used to facilitate DNA transfer by surface displaying the protein transduction domain of human immunodeficiency virus type 1 Tat protein (Tat pep...

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Detalles Bibliográficos
Autores principales: Xu, Hai, Bao, Xi, Wang, Yiwei, Xu, Yue, Deng, Bihua, Lu, Yu, Hou, Jibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859711/
https://www.ncbi.nlm.nih.gov/pubmed/29558962
http://dx.doi.org/10.1186/s12985-018-0955-1