Dexamethasone Down-regulates Osteocalcin in Bone Cells through Leptin Pathway

Glucocorticoid therapy, especially at higher doses, is associated with significant adverse side effects including osteoporosis. Leptin, secreted from adipose tissue, has diverse effects on bone tissue regulation. As glucocorticoids stimulate leptin synthesis and secretion directly in adipose tissue...

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Detalles Bibliográficos
Autores principales: Chen, Shu-Mei, Peng, Yi-Jen, Wang, Chih-Chien, Su, Sui-Lung, Salter, Donald M, Lee, Herng-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859774/
https://www.ncbi.nlm.nih.gov/pubmed/29559840
http://dx.doi.org/10.7150/ijms.21881

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859774/
https://www.ncbi.nlm.nih.gov/pubmed/29559840
http://dx.doi.org/10.7150/ijms.21881

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