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pH-mediated upregulation of AQP1 gene expression through the Spi-B transcription factor

BACKGROUND: Bicarbonate-based peritoneal dialysis (PD) fluids enhance the migratory capacity and damage-repair ability of human peritoneal mesothelial cells by upregulating AQP1. However, little is known about the underlying molecular mechanisms. RESULTS: Here we used HEK-293T cells to investigate t...

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Detalles Bibliográficos
Autores principales: Zhai, Yihui, Xu, Hong, Shen, Qian, Schaefer, Franz, Schmitt, Claus P., Chen, Jing, Liu, Haimei, Liu, Jialu, Liu, Jiaojiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859780/
https://www.ncbi.nlm.nih.gov/pubmed/29554889
http://dx.doi.org/10.1186/s12867-018-0104-9