Altered levels of the splicing factor muscleblind modifies cerebral cortical function in mouse models of myotonic dystrophy

Myotonic dystrophy (DM) is a progressive, multisystem disorder affecting skeletal muscle, heart, and central nervous system. In both DM1 and DM2, microsatellite expansions of CUG and CCUG RNA repeats, respectively, accumulate and disrupt functions of alternative splicing factors, including musclebli...

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Detalles Bibliográficos
Autores principales: Chen, Gang, Carter, Russell E., Cleary, John D., Reid, Tammy S., Ranum, Laura P., Swanson, Maurice S., Ebner, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859959/
https://www.ncbi.nlm.nih.gov/pubmed/29331264
http://dx.doi.org/10.1016/j.nbd.2018.01.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859959/
https://www.ncbi.nlm.nih.gov/pubmed/29331264
http://dx.doi.org/10.1016/j.nbd.2018.01.003

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