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Assessing sufficiency and necessity of enhancer activities for gene expression and the mechanisms of transcription activation
Enhancers are important genomic regulatory elements directing cell type-specific transcription. They assume a key role during development and disease, and their identification and functional characterization have long been the focus of scientific interest. The advent of next-generation sequencing an...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859963/ https://www.ncbi.nlm.nih.gov/pubmed/29491135 http://dx.doi.org/10.1101/gad.310367.117 |