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Model-based branching point detection in single-cell data by K-branches clustering

MOTIVATION: The identification of heterogeneities in cell populations by utilizing single-cell technologies such as single-cell RNA-Seq, enables inference of cellular development and lineage trees. Several methods have been proposed for such inference from high-dimensional single-cell data. They typ...

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Detalles Bibliográficos
Autores principales: Chlis, Nikolaos K, Wolf, F Alexander, Theis, Fabian J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860029/
https://www.ncbi.nlm.nih.gov/pubmed/28582478
http://dx.doi.org/10.1093/bioinformatics/btx325