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Exploring spatially adjacent TFBS-clustered regions with Hi-C data

MOTIVATION: Transcription factor binding sites (TFBSs) are clustered in the human genome, forming the TFBS-clustered regions that regulate gene transcription, which requires dynamic chromatin configurations between promoters and distal regulatory elements. Here, we propose a regulatory model called...

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Detalles Bibliográficos
Autores principales: Chen, Hebing, Jiang, Shuai, Zhang, Zhuo, Li, Hao, Lu, Yiming, Bo, Xiaochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860062/
https://www.ncbi.nlm.nih.gov/pubmed/28472433
http://dx.doi.org/10.1093/bioinformatics/btx282