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An improved compound Poisson model for the number of motif hits in DNA sequences

MOTIVATION: Transcription factors play a crucial role in gene regulation by binding to specific regulatory sequences. The sequence motifs recognized by a transcription factor can be described in terms of position frequency matrices. When scanning a sequence for matches to a position frequency matrix...

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Detalles Bibliográficos
Autores principales: Kopp, Wolfgang, Vingron, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860096/
https://www.ncbi.nlm.nih.gov/pubmed/28961747
http://dx.doi.org/10.1093/bioinformatics/btx539