PI4KIIα regulates insulin secretion and glucose homeostasis via a PKD-dependent pathway

Insulin release by pancreatic β cells plays a key role in regulating blood glucose levels in humans, and to understand the mechanism for insulin secretion may reveal therapeutic strategies for diabetes. We found that PI4KIIα transgenic (TG) mice have abnormal glucose tolerance and higher serum gluco...

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Detalles Bibliográficos
Autores principales: Zhang, Lunfeng, Li, Jiangmei, Zhang, Panpan, Gao, Zhen, Zhao, Yingying, Qiao, Xinhua, Chen, Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860104/
https://www.ncbi.nlm.nih.gov/pubmed/29577067
http://dx.doi.org/10.1007/s41048-018-0049-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860104/
https://www.ncbi.nlm.nih.gov/pubmed/29577067
http://dx.doi.org/10.1007/s41048-018-0049-z

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