Role of DNA Methylation in Type 2 Diabetes Etiology: Using Genotype as a Causal Anchor

Several studies have investigated the relationship between genetic variation and DNA methylation with respect to type 2 diabetes, but it is unknown if DNA methylation is a mediator in the disease pathway or if it is altered in response to disease state. This study uses genotypic information as a cau...

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Detalles Bibliográficos
Autores principales: Elliott, Hannah R., Shihab, Hashem A., Lockett, Gabrielle A., Holloway, John W., McRae, Allan F., Smith, George Davey, Ring, Susan M., Gaunt, Tom R., Relton, Caroline L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2017
Materias:
Genetics/Genomes/Proteomics/Metabolomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860189/
https://www.ncbi.nlm.nih.gov/pubmed/28246294
http://dx.doi.org/10.2337/db16-0874

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860189/
https://www.ncbi.nlm.nih.gov/pubmed/28246294
http://dx.doi.org/10.2337/db16-0874

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