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Role of DNA Methylation in Type 2 Diabetes Etiology: Using Genotype as a Causal Anchor
Several studies have investigated the relationship between genetic variation and DNA methylation with respect to type 2 diabetes, but it is unknown if DNA methylation is a mediator in the disease pathway or if it is altered in response to disease state. This study uses genotypic information as a cau...
Autores principales: | Elliott, Hannah R., Shihab, Hashem A., Lockett, Gabrielle A., Holloway, John W., McRae, Allan F., Smith, George Davey, Ring, Susan M., Gaunt, Tom R., Relton, Caroline L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860189/ https://www.ncbi.nlm.nih.gov/pubmed/28246294 http://dx.doi.org/10.2337/db16-0874 |
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