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JEPEGMIX2: improved gene-level joint analysis of eQTLs in cosmopolitan cohorts

MOTIVATION: To increase detection power, researchers use gene level analysis methods to aggregate weak marker signals. Due to gene expression controlling biological processes, researchers proposed aggregating signals for expression Quantitative Trait Loci (eQTL). Most gene-level eQTL methods make st...

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Detalles Bibliográficos
Autores principales: Chatzinakos, Chris, Lee, Donghyung, Webb, Bradley T, Vladimirov, Vladimir I, Kendler, Kenneth S, Bacanu, Silviu-Alin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860197/
https://www.ncbi.nlm.nih.gov/pubmed/28968763
http://dx.doi.org/10.1093/bioinformatics/btx509